Lab Activity Blood Type Pedigree Mystery Answer Key Upd -

If you are a teacher, you want students to discover the answer, not copy it. Here is a scaffolding strategy using this key:

Let us assume you are using the widely circulated "Pedigree Investigation: The Bloodline Thief" (Version 3.0, updated 2024).

Why does this article stress "UPD"? Because many online answer keys from 2010-2018 contain three major errors that we have corrected here:

| Old Answer Key (Error) | Updated (UPD) Correct Answer | Why the Change | | :--- | :--- | :--- | | "Type AB blood is a universal recipient for antigen transfer." | Type AB is universal recipient for RBC transfusions (no antibodies), but NOT for plasma donation. | Clarity on transfusion medicine. | | "Two Type A parents can only have Type A or O children." | Correct, but old keys missed that IAi x IAi yields 25% O. | Many keys forgot the recessive i. | | "Blood type is solely determined by ABO gene." | Updated keys note the H antigen (Bombay phenotype) but state: "Assume standard ABO for this lab." | Prevents advanced students from overcomplicating. | | Pedigree symbols: Used shading for "blood type O." | Use shading only for the trait of interest (e.g., rare allele or disease). For ABO, write genotype inside symbol. | Standardization with NIH pedigree guidelines. |

Before revealing the answer key, we must align on the updated (UPD) genetic rules. The old keys sometimes ignore the cis-AB or Bombay phenotype, but for standard high school level, we stick to the core rules: lab activity blood type pedigree mystery answer key upd

| Blood Type (Phenotype) | Possible Genotypes | Antigen on RBC | Antibody in Plasma | | :--- | :--- | :--- | :--- | | A | IAIA or IAi | A antigen | Anti-B | | B | IBIB or IBi | B antigen | Anti-A | | AB | IAIB | A and B antigens | None | | O | ii | None (H antigen only) | Anti-A and Anti-B |

Critical Rule for Pedigrees:

If Victoria is IAIA, she can only pass an IA allele. For Louis to be Type O (ii), he must receive i from father and i from mother. But mother has no i. Contradiction. Unless:

Final Answer Key Box:

Conclusion: Prince Louis is not the biological offspring of Queen Victoria and King Albert. The pedigree shows a non-paternity event or hospital mix-up. The true parents of a Type O child must both carry an i allele. Since Victoria is IAIA, Louis must belong to another family.

| Claimant | Claimed Blood Type | Possible Biological Child? | Explanation | | :--- | :--- | :--- | :--- | | Claimant 1 | Type A | YES | Genotype AO – Received A from father, O from mother. | | Claimant 2 | Type B | YES | Genotype BO – Received B from father, O from mother. | | Claimant 3 | Type O | NO | Genotype OO would require father to donate an O, but AB father has no O allele. |

Final Verdict: Claimants 1 and 2 are possible biological children. Claimant 3 is excluded.

Use Google Slides or Jamboard. Give each student a drag-and-drop pedigree where they must place the correct genotype (AA, AO, BB, BO, AB, OO) inside each symbol.