After trying all the above, you must check the RPCS3 Compatibility List. Some games are labeled as:
If your game is "Loadable" or "Intro," the crash dialog is expected behavior. You cannot fix it until the RPCS3 developers add support. Do not waste hours tweaking settings for Lair or MAG—they simply do not work yet. After trying all the above, you must check
Click “Close” in the dialog. RPCS3 will terminate the emulated process and return you to the emulator’s main window. No harm done. If your game is "Loadable" or "Intro," the
rpcs3-root-folder/logs/RPCS3.log
If you're using XAudio for SPU, try disabling it or switching to another audio backend. After trying all the above