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EPHX1 is a homodimeric enzyme primarily located in the endoplasmic reticulum of liver cells, though it is also present in kidneys, lungs, and testes. Each subunit (~53 kDa) contains an alpha/beta hydrolase fold, with a catalytic triad—Asp226, His431, and Asp495—that is essential for activity. Unlike cytochrome P450s (which generate epoxides), EPHX1 acts on existing epoxide substrates. In many regions, reliable internet is not guaranteed
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| Type of PDF | Purpose | Ideal for... | | :--- | :--- | :--- | | Course Handout (Polycopié) | Word-for-word lecture replacement | Daily study & exam review | | Mind Maps & Pathways | Visual simplification of cycles | Last-minute revision | | Multiple Choice Question (MCQ) Banks | Self-testing & application | Exam simulation | | Lab Techniques Guide | Chromatography, electrophoresis, spectrophotometry | Practical exams (TPs) | | Corrigés (Answer Keys) | Understanding marking schemes | Avoiding common mistakes |
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