Now that you have your WUX file loaded, you need performance. Vanilla BOTW on Cemu runs poorly on integrated graphics. Here is the recommended setup.
Right-click BOTW in Cemu and go to Graphics Packs. Download the community packs via the Cemu UI. Enable:
If you want to use mods like the Second Wind mod or graphic packs manually, having the game in a folder structure is easier than a single WUX file.
Some users prefer to convert WUX files into other formats for easier file management or modding.